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Effects of Low Levels of Dietary Cadmium in Animals—A Review¹

ABSTRACT

Cadmium is a toxic metal commonly found in small quantities in animal and human foods. The possible effects on domestic animal and human health from exposure over long periods to low (0–10 ppm) dietary concentrations of the metal is currently a cause for concern. Experimental data from laboratory animals indicate that low dietary concentrations of the metal will impair growth, cause hypertension and sodium retention, and produce adverse effects on some enzyme systems, reproduction, and tissue levels of some essential metals. Some of these toxic effects may be prevented by supplementary levels of iron, copper, zinc, selenium, and manganese in the diet.

Key Words: toxic effects • hypertension • enzymes • growth • reproduction • sodium retention • interactions

¹ Contribution of the Veterinary Toxicology and Entomology Research Lab., Agric. Res. Serv., USDA, P. O. Drawer GE, College Station, TX 77840.

² Research Animal Scientist, USDA-ARS. U.S. Sheep Exp. Stn., Dubois, ID 83423.

Received for publication November 8, 1976.